Hey, Amy. I started on Cimzia 7 weeks ago. It took a good three to four weeks before I started feeling the effects. And at this point, I consider Cimzia a major win for me. I'm now back to doing most of the things that I couldn't do just two months ago. For instance, I just spent 8 hours yesterday putting together a new gas grill - lots of little screws, nuts, bolts, lifting heavy pieces, lying on my back to access small spaces, etc. Yes, I'm bloody sore today, but I would have crippled myself previously, trying to even do half that effort.

My energy is also now much higher. FYI, the day that I started Cimzia, I made a major change in my life. I started wearing a fitbit (www.fitbit.com) and keeping track of all my exercise and my food. I've now dropped 24 lbs - so the change in diet and weight loss also probably figure into the increased energy and lessening of AS symptoms and pain. I cut out sugar entirely, removed bread (bread is my comfort food), reduced my portion sizes and generally just restocked my larder with more healthy foods. It's not a diet - it's just sensible eating. I highly recommend it.   :)

Good luck to you - I'm really interested in hearing how you do on Cimzia.

Time frame to feel the effects of this class of drug is anywhere from 1 week to 6 months. Usually your doctor will keep you on whatever you were taking until out kicks in unless there is an interaction or you has to quit the previous drug sure to a bad reaction.